University of California, San Diego Leichtag Room 283 9500 Gilman Drive, 0721 La Jolla, CA 92093-0721   Email :   Phone :  (858) 822-4007  Fax :  (858) 822-5888

University of California, San Diego
Leichtag Room 283
9500 Gilman Drive, 0721
La Jolla, CA 92093-0721

Email :
Phone : (858) 822-4007
Fax : (858) 822-5888


Sanyal A, Chen AJ, Nakayasu ES, Lazar CS, Zbornik EA, Worby CA, Koller A, Mattoo S. A novel link between Fic (filamentation induced by cAMP)-mediated adenylylation/AMPylation and the unfolded protein response. J Biol Chem. 2015 Mar 27;290(13):8482-99. doi: 10.1074/jbc.M114.618348. Epub 2015 Jan 19. PMID: 25601083

Worby CA, Dixon JE. Unpacking the unfolded protein response. Cell. 2014 Sep 11;158(6):1221-4. doi: 10.1016/j.cell.2014.08.025. PMID: 25215479

Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE Jr, Xiao J, Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon JE, Yeo CY, Whitman M. A secreted tyrosine kinase acts in the extracellular environment. Cell. 2014 Aug 28;158(5):1033-44. doi: 10.1016/j.cell.2014.06.048. PMID: 25171405

Worby CA, Dixon JE. PTEN. Annu Rev Biochem. 2014;83:641-69. [PMID: 24905788][4]

Teh PG, Chen MJ, Engel JL, Worby CA, Manning G, Dixon JE, Zhang J. Identification of a Mammalian-type Phosphatidylglycerophosphate Phosphatase in the Eubacterium Rhodopirellula baltica. J Biol Chem. 2013 Feb 15;288(7):5176-85. PMID: 23293031

Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon JE. Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science. 2012 Jun 1;336(6085):1150-3. PMID: 22582013

Mattoo S, Durrant E, Chen MJ, Xiao J, Lazar CS, Manning G, Dixon JE, Worby CA. Comparative analysis of Histophilus somni IbpA with other FIC enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem. 2011 Jul 27. PMID: 21795713

Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. Mitochondrial Phosphatase PTPMT1 Is Essential for Cardiolipin Biosynthesis. Cell Metabolism. 2011 Jun 8;13(6):690-700. PMID: 21641550

Worby CA, Dixon JE. Glycogen synthase: an old enzyme with a new trick. Cell Metabolism. 2011 Mar 2;13(3):233-4. PMID: 21356510

Xiao J, Worby CA, Mattoo S, Sankaran B, Dixon JE. Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol. 2010 Aug;17(8):1004-10. PMID: 20622875

Gentry MS, Dixon JE, Worby CA. Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci. 2009 Dec;34(12):628-39. PMID: 19818631

Worby CA, Mattoo S, Kruger RP, Corbeil LB, Koller A, Mendez JC, Zekarias B, Lazar C, Dixon JE. The fic domain: regulation of cell signaling by adenylylation. Mol Cell. 2009 Apr 10;34(1):93-103. PMID:19362538. Authors contributed equally to this work.

Iwasaki H, Murata Y, Kim Y, Hossain MI, Worby CA, Dixon JE, McCormack T, Sasaki T, Okamura Y. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):7970-5. PMID: 18524949

Worby CA, Gentry MS, Dixon JE. Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem 2008 Feb 15;283(7):4069-76. PMID: 18070875